2026
Gong S.†, Qiu J.†, Huang F.†, Alp Y., Krishna J., Strieter E.R., Thayumanavan S.* Incorporation of Functional Proteins on Cellular Surfaces via Artificial Extracellular Vesicles for Plasma Membrane Reprogramming. J. Am. Chem. Soc. ASAP.
2025
Shestoperova E.I., Ivanov D.G., Chien L., Strieter E.R.*
Computationally Driven Top-Down Mass Spectrometry of Ubiquitinated Proteins.
bioRxiv (2025). doi:10.1101/2025.07.24.666707.
Li Y., Chang L., Patel R., Shestoperova E.I., Du J., Das C., Strieter E.R.*
Site-Specific Nanobody Inhibitors of the Proteasomal Deubiquitinase UCH37.
bioRxiv (2025). doi:10.1101/2025.08.11.669711.
Okon A., Morgunov A., Yang J., Petri Y.D., Kilgore H.R., Li Y., Strieter E.R., Raines R.T.*
Hydrophilic α-Aryl-α-Diazonamides for Protein Esterification.
Synlett (2025). doi:10.1055/s-0043-1775499.
Giancola J.B., Okon A., Li Y., Strieter E.R., Raines R.T.*
Cytosolic Delivery of Functional Ubiquitin.
Journal of Peptide Science 31 (2025): e70026. doi:10.1002/psc.70026.
Schafer J.M., Muli C.S., Heikal R.A., Dyba M.A., Tarasov S.G., Stratton M.M., Strieter E.R., Walters K.J.*
Optimized Mammalian Expression System for the Ubiquitin E3 Ligase E6AP/UBE3A.
Protein Expression and Purification 228 (2025): 106661. doi:10.1016/j.pep.2025.106661.
2024
Okon A., Yang J., Giancola J.B., Molina O.J., Sayers J., Cheah K.M., Strieter E.R., Raines R.T.*
Facile Access to Branched Multi-Specific Proteins.
Bioconjugate Chemistry 35 (2024): 954–962. doi:10.1021/acs.bioconjchem.4c00162.
2023
Shestoperova E.I., Strieter E.R.*
Uncovering DUB Selectivity Through Ion-Mobility-Based Assessment of Ubiquitin Chain Isomers.
Analytical Chemistry 95 (2023): 17416–17423. doi:10.1021/acs.analchem.3c04622.
Shestoperova E.I., Ivanov D.G., Strieter E.R.*
Quantitative Analysis of Diubiquitin Isomers Using Ion-Mobility Mass Spectrometry.
Journal of the American Society for Mass Spectrometry 34 (2023): 931–938. doi:10.1021/jasms.3c00016.
2022
Fan R., Li Y., Du J., Chang L., Strieter E.R., Andrew T.L.
A Strategy for Accessing Nanobody-Based Electrochemical Sensors for Analyte Detection in Complex Media.
ECS Sensors Plus (2022). doi:10.1149/2754-2726/ac5b2e.
Date S.S., Xu P., Hepowit N.L., Diab N.S., Best J., Xie B., Du J., Strieter E.R., Parker Jackson L., MacGurn J.A., Graham T.R.*
Ubiquitination Drives COPI Priming and Golgi SNARE Localization.
eLife 11 (2022): e80911.
Du J., Babik S., Li Y., Deol K.K., Eyles S.J., Fejzo J., Tonelli M., Strieter E.R.*
A Cryptic K48 Chain Binding Site on UCH37 is Required for its Role in Proteasomal Degradation.
eLife 11 (2022): e76100.
2021
Deol K.K., Strieter E.R.*
The Ubiquitin Proteoform Problem.
Current Opinion in Chemical Biology 63 (2021): 95–104. (Review)
Shorkey S.A., Du J., Pham R., Strieter E.R., Chen M.*
Real-Time and Label-Free Measurement of Deubiquitinase Activity with a MspA Nanopore.
ChemBioChem 22 (2021): 2688–2692.
Fan R.†, Du J.†, Park K.-W.†, Chang L., Strieter E.R., Andrew T.L.
Immobilization of Nanobodies with Vapor-Deposited Polymer Encapsulation for Robust Biosensors.
ACS Applied Polymer Materials 3 (2021): 2561–2567.
2020
Deol K.K., Crowe S.O., Du J., Bisbee H.A., Guenette R.G., Strieter E.R.*
Proteasome-Bound UCH37/UCHL5 Debranches Ubiquitin Chains to Promote Degradation.
Molecular Cell 80 (2020): 796–809.
Deol K.K., Eyles S., Strieter E.R.*
Quantitative Middle-Down MS Analysis of Parkin-Mediated Ubiquitin Chain Assembly.
Journal of the American Society for Mass Spectrometry 31 (2020): 1132–1139.
2019
Deol K.K., Lorenz S., Strieter E.R.
Enzymatic Logic of Ubiquitin Chain Assembly.
Frontiers in Physiology 10 (2019): 835. (Review)
Liu J., Li Y., Deol K.K., Strieter E.R.*
Synthesis of Branched Tri-Ubiquitin Active-Site Directed Probes.
Organic Letters 21 (2019): 6790–6794.
Ries L.K., Sander B., Deol K.K., Letzelter M.A., Strieter E.R., Lorenz S.*
Analysis of Ubiquitin Recognition by the HECT Ligase E6AP Provides Insight into Linkage Specificity.
Journal of Biological Chemistry 294 (2019): 6113–6129.
2018
Chang L., Strieter E.R.*
Reprogramming a Deubiquitinase into a Transamidase.
ACS Chemical Biology 13 (2018): 2808–2818.
Du J., Strieter E.R.*
A Fluorescence Polarization-Based Competition Assay for Measuring Interactions between Unlabeled Ubiquitin Chains and UCH37•RPN13.
Analytical Biochemistry 550 (2018): 84–89.
2017
Rana A.S.J.B., Ge Y., Strieter E.R.*
Ubiquitin Chain Enrichment Middle-Down Mass Spectrometry Reveals Cell-Cycle Dependent Formation of Lys11/Lys48 Branched Ubiquitin Chains.
Journal of Proteome Research 16 (2017): 3363–3369.
Bowerman S.†, Rana A.S.J.B.†, Rice A.M., Pham G.H., Strieter E.R., Wereszczynski J.
Determining Atomistic SAXS Models of Tri-Ubiquitin Chains from Bayesian Analysis of Accelerated Molecular Dynamics.
Journal of Chemical Theory and Computation 13 (2017): 2418–2429.
Crowe S.O.†, Rana A.S.J.B.†, Deol K.K., Ge Y., Strieter E.R.*
Ubiquitin Chain Enrichment Middle-Down Mass Spectrometry (UbiCHEM-MS) Enables Characterization of Branched Ubiquitin Chains In Cellulo.
Analytical Chemistry 89 (2017): 4428–4434.
2016
Whedon S.E., Nagula M., Rana A.S.J.B., Senger N., Weller C.E., Turecek F., Strieter E.R., Chatterjee C.
Selenocysteine as a Latent Bioorthogonal Electrophilic Probe for Deubiquitylating Enzymes.
Journal of the American Chemical Society 138 (2016): 13774–13777.
Crowe S.O., Pham G.H., Ziegler J.C., Deol K.K., Guenette R.G., Ge Y., Strieter E.R.*
Subunit-Specific Labeling of Ubiquitin Chains Using Sortase: Insights into the Selectivity of Deubiquitinases.
ChemBioChem 17 (2016): 1525–1531.
Pham G.H.†, Rana A.S.J.B.†, Korkmaz E.N.†, Trang V.H., Cui Q., Strieter E.R.*
Comparison of Native and Non-Native Ubiquitin Oligomers Reveals Analogous Structures and Reactivities.
Protein Science 25 (2016): 456–471.
2015
Strieter E.R.*, Andrew T.L.
Restricting the ψ Torsion Angle Has Stereoelectronic Consequences on a Scissile Bond: An Electronic Structure Analysis.
Biochemistry 54 (2015): 5748–5756.
Pham G.H., Strieter E.R.*
Peeling Away the Layers of Ubiquitin Signaling Complexities with Synthetic Ubiquitin-Protein Conjugates.
Current Opinion in Chemical Biology 28 (2015): 57–65. (Review)
2014
Shekhawat S.S.†, Pham G.H.†, Prabakaran J., Strieter E.R.*
Simultaneous Detection of Distinct Ubiquitin Chain Topologies by ¹⁹F NMR.
ACS Chemical Biology 9 (2014): 2229–2236.
Valkevich E.M., Sanchez N.A., Ge Y., Strieter E.R.*
Middle-Down Mass Spectrometry Enables Characterization of Branched Ubiquitin Chains.
Biochemistry 53 (2014): 4979–4989.
Trang V.H., Rodgers M.L., Boyle K.J., Hoskins A.A., Strieter E.R.
Chemoenzymatic Synthesis of Bifunctional Polyubiquitin Substrates for Monitoring Ubiquitin Chain Remodeling.
ChemBioChem 15 (2014): 1563–1568.
Shrestha K., Ronau J.A., Davies C.W., Guenette R.G., Strieter E.R., Paul L.N., Das C.*
Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product.
Biochemistry 53 (2014): 3199–3217.
2013
Hebert A.S., Merrill A.E., Bailey D.J., Still A.J., Westphall M.S., Strieter E.R., Pagliarini D.J., Coon J.J.*
Neutron-Encoded Mass Signatures for Multiplexed Proteome Quantification.
Nature Methods 10 (2013): 332–334.
2012
Strieter E.R.*, Korasick D.A.
Unraveling the Complexity of Ubiquitin Signaling.
ACS Chemical Biology 7 (2012): 52–63. (Review)
Trang V.H., Valkevich E.M., Minami S., Chen Y.-C., Ge Y., Strieter E.R.*
Nonenzymatic Polymerization of Ubiquitin: Single-Step Synthesis and Isolation of Discrete Ubiquitin Oligomers.
Angewandte Chemie International Edition 51 (2012): 13085–13088.
Valkevich E.M., Guenette R.G., Sanchez N.A., Chen Y.-C., Ge Y., Strieter E.R.*
Forging Isopeptide Bonds Using Thiol–Ene Chemistry: Site-Specific Coupling of Ubiquitin Molecules for Studying the Activity of Isopeptidases.
Journal of the American Chemical Society 134 (2012): 6916–6919.